Efficacy of Albaconazole against Candida albicans in a Vaginitis Model
نویسندگان
چکیده
منابع مشابه
Efficacy of ravuconazole in a murine model of vaginitis by Candida albicans.
BACKGROUND The incidence of vulvovaginal candidiasis, a common infection among healthy women primarily caused by the yeast Candida albicans, has increased significantly in recent years. AIMS The purpose of this study was to compare the efficacy of ravuconazole (RVC) and fluconazole (FLC) in the treatment of experimental C. albicans vaginitis. METHODS Forty isolates of C. albicans were scree...
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Introduction: Candida albicans is one of the most common causes of vaginitis and one of the most important reasons for women to visit health centers. The aim of this study was to determine Candida albicans infection and its related factors in women in Kazerun. Methods: This cross-sectional study was performed in 2017 on 150 samples extracted from the laboratory. Swab specimens were prepared fr...
متن کاملEffects of beta-glucan in a mice model of vaginitis by candida albicans
Methods Fifty four Balb/C mice of 7 to 10 weeks old under influence of estrogen were inoculated with 5x10 stationaryphase blastoconidia of C. albicans, intravaginally. The mice were divided in three groups, treated with glucan vaginally (5mg/mL) and intraperitoneally (1mg/mL), and the control group that received saline, intraperitoneally. Vaginal lavage was obtained on days 2, 5, 8 e 10 after i...
متن کاملTherapeutic efficacy of voriconazole against a fluconazole-resistant Candida albicans isolate in a vaginal model.
BACKGROUND The purpose of this study was to assess the therapeutic efficacy of oral versus intravaginal voriconazole and compare it with fluconazole for the treatment of experimental vaginitis caused by a fluconazole-resistant Candida albicans isolate. METHODS Mice were treated with voriconazole at 5, 10 and 20 mg/kg once a day and 20 mg/kg twice a day or with fluconazole at 20 mg/kg once or ...
متن کاملA murine model of Candida glabrata vaginitis.
Vaginal Candida glabrata infections have increased significantly in recent years and are particularly common in women with uncontrolled diabetes mellitus. Efforts to understand the pathogenesis and treatment of this infection have been hindered by the lack of experimental animal models. Before onset of hyperglycemia, nonobese diabetic (NOD) mice inoculated intravaginally with clinical C. glabra...
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ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 2009
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.00565-09